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Juniperus communis - Juniper
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September 6, 1999
JUNIPER
Juniperus communis - Family Cupressaceae
Synonyms
Ginepro, Genevrier, Enebro, Gemeiner Wachholder.
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Description
This evergreen will attain heights of 2-5 m. Its prostrate branches
growing closely together. The leaves narrow, 12mm long and in whorls of
three, deep green. The flowers are dioecious, with staminate catkins, and
pistillate cones. The nearly globular fruit is 8mm and blackish purple,
ripening in the second year. The berries have an aromatic odor and sweet
taste.
Part Used
ripe berries (2 1/2 years old).
ConstituentsThe berries contain between 0.2 and 3.4% (usually 1-2%)
volatile oil. The volatile oil of juniper consists of 50% monoterpene
alcohols including 1-terpinen-4-ol, alpha-pinene, myrcene, sabinene,
camphene, and minor amounts of limonene, p-cymene, gamma-terpinene, beta-pinene,
alpha-thujene and small amounts of sesquiterpenes including candinene and
esters. It also contains juniperin, resin (ca 10%); glucuronic acid;
catechins, proanthocyanidins; fatty acids (lauric, palmitic, oleic,
linoleic and others), sterols (sitaosterol, campesterol, cholesterol and
others), gallotannins; geijerone; flavonoid( rutin, isoquerictrin and
others) and a number of diterpenes.(1-5)
Mode of Action
The active diuretic principles of juniper berry resides in the volatile
oil, mostly terpinen-4-ol..This action is most likely a local irritant.
The oils are probably the source of the antiviral, antibiotic and
antifungal properties. The volatile oil content of the berries goes down
as they ripen and thus reduces activity level.(6) During ripening volatile
oil is changed to resin.(7,8) The diuretic action of juniper is created by
increased glomerular filtration rate.(9)
The oils has an antispasmolytic effect on smooth muscles. Juniper berries
can be used as a gastrointestinal antiseptic and mild irritant. This is
probably the mechanism around the berries ability to stimulate gastric
juices and appetite.(10)
In the Mediterranean area Juniper baths are used for the treatment of
neurasthenic neurosis and for the management of scalp psoriasis. In
Swedish medicine we find it being used to treat wounds and inflammatory
disease. We can find some evidence of this as it inhibits the activity of
protaglandin biosysthesis and platelet activating factor (PAF)-induced
exocytosis in vitro.(11,12)
Extract of the berries increase uterine tone and should not be ingested
during pregnancy. Antiimplantation/anti-fertility activity has been
described by many indigenous people and has shown up in rat studies, with
up to 60- 70% efficacy.(13)
Therapeutic Action
Juniper and/or its oil has been primarily used as a diuretic and a urinary
antiseptic. Juniper is also a gastrointestinal antiseptic, a urogenital
irritant, a carminative, an emmenagogue. The herb is used as a stimulant
and as a stimulating diuretic for cystitis.(14-21)
Energetics
Ayurvedic
Rasa - katu (pungent), tikta (bitter); Guna - guru (heavy), rooksha
(oily), teekshna; Veerya - ushna (hot); Vipak - katu (pungent). Action:
Kapha vat samak, lakhan sotha har, bran ropan, dipan, anuloman, grahi,
krimighan, kafa nisark, artawa janan, mutra janan.(22)
Other
Holmes lists juniper as a bit pungent, bitter and sweet, with warm and dry
properties. The secondary qualities are stimulating, decongesting,
softening, dissolving, astringing, with a sinking movement. Juniper enters
the Spleen, Kidney, Chong and Ren meridians; influencing the stomach,
intestines, bladder, kidney, uterus and skin. The organism is warmth and
fluid. Tri Dosas of increases Pita and Vayu, while lowering Kapha.(23)
Folklore
Though primarily known for its diuretic properties, juniper is also useful
in cases of flatulence,(24) to stimulate gastric acids, liver problems,
colic, intestinal worms and as a vapour steam for bronchitis.(25) It has
been used as a folk remedy for arteriosclerosis, arthritis, bronchitis,
cancer, colic, dropsy, dysentery, dyspepsia, gastroenteritis, gonorrhea,
gout, gravel, leucorrhea, lumbago, nephrosis, rheumatism, worms,
urogenital and venereal diseases.(26)
It is also mentioned in the writings of Gerard (1597), Hill (1751) and
Bigelow (1817-21). Juniper berries have been used as an antiseptic barrier
by practitioners. The technique was to suck the berries while treating
patients with infectious diseases. Native Americans made extensive use of
juniper as did Ayurvedic practitioners.(27) The eight or more subspecies
of Juniperus were used by virtually all the Native peoples of North
America. They used juniper as a vermifuge, diuretic, antiseptic and
antirheumatic.(28)
Dosage
Juniper Oil B.P.C. 1949 - 0.03 to 0.2 ml. (29,300
Juniper Berries N.F. 1935 - 4.0 grams (31)
Juniper Berries average dose - 4.0 grams (32.33)
Fluid Extract of Juniper N.F. 1935 - 4.0 ml. (34)
Juniper Spirits B.P.C. 1949 - .3 to 1.2 ml. (35,36)
Toxicity and Contraindications
Spoerke(37) reports that juniper in a single large dose produces only
catharsis but says that smaller repeated doses may produce renal damage,
personality changes and convulsions. Juniper Berry oil is nonsensitizing,
nonphototoxic, and only slightly irritating in topical application.(38)
This herb should not be taken during or if suspecting pregnancy.
Official Recognition and Medical References
Fluid extractum juniperi N.F. 1935 (39)
juniper oil n.f.1935, b.p.c. 1934 (40,41)
juniper berries n.f.1935, b.p.c. 1934 (42)
juniper spirits b.p.c. (43)
ESCOP - July 1997
Commision E - p. 155
PDR for Herbal Medicine - p. 918
References
1. Leung, A..Y. and S. Foster, Encyclopedia of Common Natural Ingredients:
Used in Food, Drugs, and Cosmetics, John Wiley & Sons, Inc., New York,
1996, p. 325-327
2. Lawrence Review of Natural Products; Juniper; Feb. 1997, p. 1-3
3. Spoerke, D.G., Herbal Medications, Ibid.
4. Spoerke, D.G., Herbal Medications, Woodbridge Press Publ. Co., Santa
Barbara, CA, 1980, p. 102.
5. Trease, G.E. and Evans, W.C., Pharmacognosy 11 ed., Bailliere Tindall,
London, 1978. p. 425.
6. Spoerke, D.G., Herbal Medications, Ibid.
7. Spoerke, D.G., Herbal Medications, Ibid.
8. Wood, H.C. and Osol, A., Dispensatory of the United States of America
23rd ed.,J.B. Lippincott, Montreal, P.Q., 1943, p. 583.
9. Racz-Kotilla, E., et al., Actiunea diurectia a fructelor de
ienupar (Juniperus communis), Farmacia 19(3), p. 165-169, 1971.
10. Leung A.Y. and Foster; Ibid
11. Lawrence review, Ibid
12. Tunon H., et al; Jour. Of Ethnopharm; 48(2) 1995; p. 61-76
13. Lawrence review, Ibid
14. The Merck Index 5th Ed., Merck & Co. Inc., Rahway, N.J., 1940. p.
203.
15 Said, H.M. (Ed.), Hamdard Pharmacopeia of Eastern Medicine,
Pharmaceutical Advisory Council of Hamdard, The Times Press, Sadar
Karachi, 1969. p. 395.
16. Wren, R.C., Potter`s New Cyclopaedia of Botanical Drugs and
Preparations, Health Science Press, Rustington, Sussex, U.K., 1975. p.
171.
17. Martindale: The Extra Pharmacopeia, The Pharmaceutical Press, London,
1941, p. 743.
18. Youngken, H.W., Textbook of Pharmacognosy, Blakiston, Toronto, 1950,
p. 127.
19. Leung, A.Y., Encyclopedia of common natural ingredients used in food,
drugs,and cosmetics, Ibid.
20. The British Pharmaceutical Codex 1934. The Pharmaceutical Press,
London,1934, p. 712.
21. Trease, G.E. and Evans, W.C., Pharmacognosy 11 Ed., Ibid.
22. Kapoor, L.D., CRC Handbook of Ayurvedic Medicinal Plants, CRC Press,
Boca Raton, FL, 1990, p. 215.
23. Holmes, P., The Energetics of Western Herbs (2 vols.), Artemis Press,
Boulder, CO, 1989, p. 213-215.
24. Grieve, M., A Modern Herbal, Jonathan Cape, London, 1931, p. 452.
25. Leung, A.Y., Ibid.
26. Duke, J.A., Ibid.
27. Kapoor, L.D., Ibid.
28. Moerman, D.E., Medicinal Plants of Native America, University of
Michigan
Museum of Anthropology, Technical Reports, Number 19, Ann Arbor,
Michigan,1986, Vol.1, p. 241.
29. Wren, R.C., Potter`s New Cyclopaedia of Botanical Drugs and
Preparations, Health Science Press, Rustington, Sussex, U.K., 1975. p.
170.
30. Martindale: The Extra Pharmacopeia, Ibid.
31. The National Formulary 6th ed., American Pharmaceutical
Association,Washington DC, 1935. p. 208.
32. Gathercoal, E.N. and Wirth, E.H., Pharmacognosy, Lea & Febiger,
Phila. PA, 1936. p. 583.
33. Youngken, H.W., Textbook of Pharmacognosy, Ibid.
34. The National Formulary 6th ed., Ibid., p. 171.
35. Wren, R.C., Ibid.
36. Martindale: The Extra Pharmacopeia, Ibid.
37 .Spoerke, D.G., Herbal Medications, Ibid.
38. Leung, A.Y., Encyclopedia of common natural ingredients used in food,
drugs, and cosmetics, Ibid.
39. The National Formulary 6th ed., Ibid.
40. Youngken, H.W., Textbook of Pharmacognosy, Ibid.
41. The British Pharmaceutical Codex 1934. Ibid.
42. The National Formulary 6th ed., Ibid., p. 207,208.
43. Martindale: The Extra Pharmacopeia, Ibid.
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